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© 1999 Bulls of Crown


Since 1999


    © 1999 BULLS OF CROWN                  SINDS 1999 / SINCE 1999            BULLSOFCROWN@GMAIL.COM




DNA(Desoxyribo Nucleic Acid)



The DNA database, important for dog breeder and owner!!!

In the last years the DNA- research undergoes a super development. Within manageable period DNA-tests will form a solution for much hereditary problems, also at our dog. Rise of fabric monsters (blood) in a so-called DNA database can play an important role.

 

What is DNA?
Just like at all live organisms also the body of dogs has been built from cells. Almost each cell has a core with in this chromosomes, the bearers of the hereditary properties. Chromosomes are elongated thin molecules, the so-called DNA (deoxyribonucleic acid).

In the DNA the hereditary code of each individual has been set out. This code stipulates which external characterise the animal has, for example to which type and to which race it belongs, but hereditary sicknesses also which and deviations carry the animal at itself. At the reproduction by each of the parents half of this code to each descendant is passed on. Using special laboratory techniques it is possible be a part of the hereditary code visible and these to compare with those of family members. Because, excluded identical twins, no two animals the same is, each animal has his own unique DNA profile.


What is a DNA database?
A DNA database is a rise (a file) in which fabric monsters of individuals are kept. Generally it concerns blood monsters, sometimes for salivas or its monsters, from which as soon as that necessary is the DNA can be freed. Those monsters become according to a determined protocol collected. It is of the largest importance that the correct identity of the animal is determined. The veterinary surgeon must the monster-nasty and check an other one closely at thus.

After the monsters are at the DNA database are handed in which divided in two halves and stored on two different locations. With that it is occurred that even if lost the material at fire or another form of supremacy would go. The stored monsters are kept during minimum twenty-five years.


The importance of a DNA database

A DNA database can be used for a number of applications.

1. DNA profiles
By (a part of) the unique hereditary code of the dog – the so-called DNA profile – is stipulate establish the identity of the dog indisputably. In contrast to a chip or tattoo which missing can touch or illegible can become, the DNA profile remains onveranderbaar and controllable present. Even if there still but a small bit fabric of the animal is available is possible the profile and therefore the identity of the dog is still stipulated. This can play a role at certain disputes (loss, robber stable, etc.). The owner is then able to tones that the animal where it concerns be nevertheless real property is. More and more owner eigenaren thus above-mentioned reason let make up at the purchase of the fabric monster for the DNA database a DNA profile of their dog simultaneously.

Breeders use the DNA profiles for their puppy purchasers, who get to copies of the DNA profiles of the parent animals so that they can let the propriety of the filiation of their puppy check, if they would want that. With that these breeders make visible that they want work entirely reliable and controllable. At the purchaser that gives an extra piece trusts.

Sometimes much money is spent at purchase of a dog parents with particular qualities or for a dog with an important filiation. The purchaser in advance will want a guarantee that he gets also the dog with filiation which him was promised. A DNA profile can him offer that certainty.


2. filiation control
For the breeding and the selection policy it is very important that the breeders and race associations have reliable filiation files. filiation data are used at the decision to breed yes or no with a certain dog. Using in the database DNA stored can, in case of doubt, the filiation of the dog rapidly and easily be checked. THE DNA becomes then compared to that of the parents and other relatives. That is especially important if there is talk of selection against hereditary lacks. If filiation would not be correct can that to serious damage to lead, both for the selection programmes and which apply the breeders for the owner eigenaren which their foresail animals use wrongfully correct yes or no for the breeding.


3. Development and validatie of new DNA-testen

In the future more and more DNA-tests will come available. With these tests can be examined if your dog is free of a hereditary deviation, if he the deviation vererft (bearer is) or sufferer is. Now it is this way that, as soon as somewhere on the world new DNA-test for a hereditary deviation come there available these must be tested firstly exhaustively. To sufficient DNA monsters to qualify for this validatie, must be frequently appealed there to the breeders and owner eigenaren of for this coming dogs (sufferers to the concerning deviation and their family members). Because the monsters must be collected especially generally for this one aim costs to that much time and money. If these monsters can be from a DNA database available that many more rapidly and much cheaper.


4. practice screening for hereditary lacks

After has appeared that new DNA-test are arranged have proven to be for application at a certain race, the question to the order is how that test must be fitted in the foresails and selection policy. For breeders it is very important as soon as possible of knowing what is the hereditary status of their dogs. They want know or their foresail animal yes or no bearer is of the deviation. When fabric monsters of the foresail animals are very rapidly stored in the DNA database can this be determined without this brings with extra efforts and costs for tests (blood purchase) with itself. With that help the advantages of new DNA-test as soon as possible to the fokkerij. Moreover the breeders get the possibility afterwards, even long after the concerning animals have died, of examining or their foresail animals yes or no bearer or sufferer were for that deviation. In a number of cases is that important information for further choices in the breeding.